Tīmeklis2024. gada 30. marts · Present results indicate that prolonged treatment with SUN affects LAMP1 and LAMP2 expression only marginally in most patients. In contrast, changes in ATP6V1B2 expression were marked and resembled irregular oscillations. Very similar changes in the expression of lysosomal membrane proteins were also … Tīmeklis2024. gada 6. janv. · LAMP1 and LAMP2 are estimated to account for approximately 50% of lysosomal membrane proteins (Eskelinen 2006 ). LAMP1 possesses a large luminal ectodomain and transmembrane domain, followed by a short C-terminal cytoplasmic tail (Fukuda 1991; Eskelinen et al. 2003 ).
LAMP1 Monoclonal Antibody (LY1C6) (MA1-164)
TīmeklisMilana Fraiberg, Zvulun Elazar, in Progress in Molecular Biology and Translational Science, 2024. 3.4 LAMP2. The LAMP2 gene is located on the Xq24 chromosome. … LAMP1 and LAMP2 glycoproteins comprise 50% of all lysosomal membrane proteins, and are thought to be responsible in part for maintaining lysosomal integrity, pH and catabolism. The expression of LAMP1 and LAMP2 glycoproteins are linked, as deficiencies in LAMP1 gene will lead to increased … Skatīt vairāk Lysosomal-associated membrane protein 1 (LAMP-1) also known as lysosome-associated membrane glycoprotein 1 and CD107a (Cluster of Differentiation 107a), is a protein that in humans is encoded by the LAMP1 Skatīt vairāk Residing primarily across lysosomal membranes, these glycoproteins consist of a large, highly glycosylated end with N-linked carbon chains on the luminal side of the membrane, … Skatīt vairāk • Cluster of differentiation Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. Skatīt vairāk LAMP1 expression on the surface of tumor cells has been observed for a number of different cancer types, particularly in highly metastatic cancers such as pancreatic cancer, colon cancer and melanoma. The structure of LAMP1 correlates with differentiation and … Skatīt vairāk • LAMP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • PDBe-KB provides an overview of all the structure information … Skatīt vairāk evernote redwood city ca
LAMP1 Polyclonal Antibody (PA1-654A) - Thermo Fisher Scientific
Tīmeklis2024. gada 18. jūl. · LAMP1 (lysosomal associated membrane protein 1) and LAMP2 are distributed among autophagic and endolysosomal organelles. Despite widespread distribution, LAMP1 is routinely used as a lysosome marker and LAMP1-positive organelles are often referred to as lysosomal compartments. Tīmeklis2008. gada 23. sept. · LAMP1 DMDM 206729915 ClinGen HGNC:6499 GenCC HGNC:6499 PTM/Processing Features Showing features for signal, chain, glycosylation, disulfide bond. Expand table Post-translational modification O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans. The glycosylation of N … TīmeklisLAMP1/CD107a Protein, Human (HEK293, Fc) is a recombinant human CD107a expressed in HEK 293 cells with a C-Fc tag at the C-terminus. LAMP1/CD107a Protein can be used as a functional marker for the identification of natural killer cell activity [1] [2]. 研究背景. Lysosomal associated membrane protein 1 (LAMP1 or CD107a) is a … evernote release notes