WebMar 5, 2024 · Because reprogramming of NG2 glia also reduces glial scarring, the precise contribution of new neurons to functional recovery remains to be determined. Dissection … WebApr 15, 2024 · Cardiac diseases are the foremost cause of morbidity and mortality worldwide. The heart has limited regenerative potential; therefore, lost cardiac tissue cannot be replenished after cardiac injury. Conventional therapies are unable to restore functional cardiac tissue. In recent decades, much attention has been paid to regenerative medicine …
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WebSep 1, 2024 · The current proposal will focus on NG2 glia, another major component of the glial scar. Our preliminary data indicate that they can be in vivo reprogrammed to become neurogenic. We here propose to determine the molecular and cellular mechanisms underlying the reprogramming process of NG2 glia in adult mouse. WebNov 7, 2024 · In vivo cell fate reprogramming has emerged as a new way of understanding plasticity and as a potential therapeutic approach for treating neural injuries and … gold eagle fuel system cleaner
New potential for functional recovery after spinal cord injury
WebAug 24, 2024 · ) could affect reprogramming in vivo. NG2-Cre mice received a unilateral 6-OHDA toxin injection into the medial forebrain bundle (mfb lesion, n = 9), which produced a substantial loss of DA neurons in the SNc (Figures S3A and S3B) and subsequent loss of their projections to the dorsolateral striatum. Littermate control animals were left intact ... WebFeb 25, 2024 · In vivo reprogramming of NG2 glia enables adult neurogenesis and functional recovery following spinal cord injury February 2024 DOI: 10.1016/j.stem.2024.02.009 Authors: Wenjiao Tai University... WebJan 9, 2024 · In vivo reprogramming of pathogenic lung TNFR2. +. cDC2s by IFNβ inhibits HDM-induced asthma. Sci Immunol. 2024 Jul 9;6 (61):eabi8472. doi: … gold did chain